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digzyme has transformed the enzyme development process, which was once dependent on chance, with its unique technology.
Leveraging AI analysis to interpret the vast amount of life science research data accumulated globally, we efficiently design genes for enzymes suitable for industrial applications.
digzyme Moonlight™
Customized Enzyme 'Discovery' to Meet Specific Needs
We conduct enzyme discovery, a primary challenge in bioprocess development. Our analysis system searches and proposes functional enzymes from the vast global life science research data, targeting specific chemical reactions.
digzyme Spotlight™
Unique Enzyme Library Tailored for Industrial Applications
Addressing the challenges of enzyme industrialization, AI proposes enhancements to enzyme functionality. It predicts crucial variants for improving functions (such as increased activity or heat resistance) from the sequence information of the target enzyme.
digzyme Designed Library™
Unique Enzyme Library Tailored for Industrial Applications
We have accumulated enzymes designed using our proprietary bioinformatics methods, such as digzyme Moonlight™ and digzyme Spotlight™. This allows us to quickly transition enzymes that meet specific needs into production.
TechBlog
digzyme's Expertise
List of Enzymes with Development Experience :
CoA Ligases
Cyclases
Decarboxylases
Dehalogenases
Esterases
Glycosyltransferases
Hydrolases
Methyltransferases
Peroxidases (P450s)
Phosphotransferases
Polyketide synthases (PKSs)
Prenyltransferases
List of Information Analysis Technologies :
- Chemoinformatics
- Retrosynthetic analysis
Reaction similarity search - Genomeinformatics
- Sequence similarity search
Phylogenetic analysis
Metagenomic analysis - 3D structure analysis
- Homology modeling
de novo modeling
Ligand-enzyme docking
Polymer-enzyme docking
Molecular dynamics
Free energies calculations
QM/MM
Enzyme pocket prediction
Enzyme multimerization prediction - Enzyme Improvement
- Codon optimization
Improved mutant prediction
Ancestral sequence reconstruction